Giannì Costanza

• 2011: Laurea in Medicina e Chirurgia presso Università Sapienza Roma
• 2102-2014: Research-Fellowship presso il Martinos Center of Biomedical Imaging, Harvard Medical School, Boston, MA (USA)
• 2018: Specializzazione in Radiodiagnostica presso Università Sapienza Roma
• 2022: Dottorato di Ricerca in Neuroscienze Clinico-sperimentali presso Università Sapienza Roma

• Ricercatore a tempo determinato di tipo A presso Università Sapienza Roma
• Consulente Neuroradiologo IRCCS Neuromed dal 2019

Applicazione di tecniche avanzate di risonanza magnetica strutturale e funzionale allo studio di patologie neurologiche quali Sclerosi Multipla e Disordini del Movimento.

• Focal Dystonia: Functional Connectivity Changes in Cerebellar-Basal Ganglia-Cortical Circuit and Preserved Global Functional Architecture. Giannì C, Pasqua G, Ferrazzano G, Tommasin S, De Bartolo MI, Petsas N, Belvisi D, Conte A, Berardelli A, Pantano P.Neurology. 2022 Apr 5;98(14):e1499-e1509. doi:j 10.1212/WNL.0000000000200022. Epub 2022 Feb 15.PMID: 3516901
• Relation of sensorimotor and cognitive cerebellum functional connectivity with brain structural damage in patients with multiple sclerosis and no disability. Tommasin S, Iakovleva V, Rocca MA, Giannì C, Tedeschi G, De Stefano N, Pozzilli C, Filippi M, Pantano P; INNI Network.Eur J Neurol. 2022 Mar 17. doi: 10.1111/ene.15329. Online ahead of print.PMID: 35298059
• Altered sensorimotor integration in multiple sclerosis: A combined neurophysiological and functional MRI study. Giannì C, Belvisi D, Conte A, Tommasin S, Cortese A, Petsas N, Baione V, Tartaglia M, Millefiorini E, Berardelli A, Pantano P.Clin Neurophysiol. 2021 Sep;132(9):2191-2198. doi: 10.1016/j.clinph.2021.05.028. Epub 2021 Jun 25.PMID: 34293529.
• Machine learning classifier to identify clinical and radiological features relevant to disability progression in multiple sclerosis. Tommasin S, Cocozza S, Taloni A, Giannì C, Petsas N, Pontillo G, Petracca M, Ruggieri S, De Giglio L, Pozzilli C, Brunetti A, Pantano P.J Neurol. 2021 May 10. doi: 10.1007/s00415-021-10605-7. Online ahead of print.PMID: 33970338
• A Comprehensive Approach to Disentangle the Effect of Cerebellar Damage on Physical Disability in Multiple Sclerosis. Ruggieri S, Bharti K, Prosperini L, Giannì C, Petsas N, Tommasin S, Giglio L, Pozzilli C, Pantano P.Front Neurol. 2020 Jun 30;11:529. doi: 10.3389/fneur.2020.00529. eCollection 2020.PMID: 32695059
• Multi-scale resting state functional reorganization in response to multiple sclerosis damage. Tommasin S, De Giglio L, Ruggieri S, Petsas N, Giannì C, Pozzilli C, Pantano P. Neuroradiology. 2020 Mar 18. doi: 10.1007/s00234-020-02393-0. [Epub ahead of print]. PMID: 32189024.
• Deep grey matter involvement and and altered sensory gating in multiple sclerosis. Conte A*, Giannì C*, Belvisi D, Cortese A, Petsas N, Tartaglia M, Cimino P, Millefiorini E, Berardelli A, Pantano P. Mult Scler. 2019 May 13:1352458519845287. doi: 10.1177/1352458519845287. [Epub ahead of print] PMID: 31079539
• Relation between functional connectivity and disability in multiple sclerosis: a non-linear model. Tommasin S, De Giglio L, Ruggieri S, Petsas N, Giannì C, Pozzilli C, Pantano P. J Neurol. 2018 Oct 1. doi: 10.1007/s00415-018-9075-5. [Epub ahead of print] PMID: 30276520.
• Neuroinflammatory component of gray matter pathology in multiple sclerosis. Herranz E*, Giannì C*, Louapre C, Treaba CA, Govindarajan ST, Ouellette R, Loggia ML, Sloane JA, Madigan N, Izquierdo-Garcia D, Ward N, Mangeat G, Granberg T, Klawiter EC, Catana C, Hooker JM, Taylor N, Ionete C, Kinkel RP, Mainero C. Ann Neurol. 2016 Nov;80(5):776-790.
• Beyond focal cortical lesions in MS: An in vivo quantitative and spatial imaging study at 7T. Louapre C, Govindarajan ST, Giannì C, Langkammer C, Sloane JA, Kinkel RP, Mainero C. Neurology. 2015 Nov 10;85(19):1702-9.
• A gradient in cortical pathology in multiple sclerosis by in vivo quantitative 7 T imaging. Mainero C, Louapre C, Govindarajan ST, Giannì C, Nielsen AS, Cohen-Adad J, Sloane J, Kinkel RP. Brain. 2015 Apr;138(Pt 4):932-45.
• A systematic review of factors associated with accidental falls in people with multiple sclerosis: a meta-analytic approach. Giannì C, Prosperini L, Jonsdottir J, Cattaneo D. Clin Rehabil. 2014 Feb 25;28(7):704-716.
• Escalation to natalizumab or switching among immunomodulators in relapsing multiple sclerosis. Prosperini L, Giannì C, Leonardi L, De Giglio L, Borriello G, Galgani S, Pozzilli C, Gasperini C. Mult Scler. 2012 Jan;18(1):64-71.